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for Immunochemistry
Tau is a microtubule-associated protein. It is mainly expressed in neurons of the central nervous system and regulates the stability of microtubules. In the brain of patients with Alzheimer’s disease, phosphorylated Tau aggregates and forms neurofibrillary tangles (NFTs). There is evidence suggesting that the extent of NFTs correlates with the severity of dementia. Therefore, Tau has been studied extensively to better understand the causes of Alzheimer’s disease and to develop novel therapeutics.
Studies suggest that the concentration of Tau and phosphorylated Tau in the cerebrospinal fluid is elevated in patients with Alzheimer’s disease compared with non-dementia patients.
The kit facilitates the measurement of Tau, and recognizes any Tau regardless of the state of phosphorylation.
Tau is one of the microtubule-associated proteins, which is mainly expressed in neurons of the central nervous system, and controls the stabilization of microtubules.
In the brains of Alzheimer's disease patients, it is reported that neurofibrillary tangle accumulated by phosphorylated Tau is formed, and the extent of its appearance correlates with the severity of dementia. Therefore, Tau is being studied for investigating the cause of Alzheimer's disease and developing therapeutic drugs.
This product is an ELISA kit which can easily measure Tau and recognizes all Tau regardless of phosphorylation state.
This product is for research use only. Do not administer it to human.
Maufacturer: | FUJIFILM Wako Pure Chemical Corporation |
GHS: | ![]() |
Calibration curve range | 4.1-1000 pg/mL |
Measurement sample | Human cerebrospinal fluid |
Required amount of specimen | 10 μL |
Measurement time | 3 hours |
Detection method | Light emitting system |
For 96 Tests
Antibody-coated Plate | 1 plate, 96 wells ( 8 x 12) |
Tau Standard | 1 tube |
Buffer | 60 mL |
Biotin-conjugated Antibody Solution | 100 µL |
Peroxidase-conjugated Streptavidin Solution | 100 µL |
Luminescent Reagent 1 | 6 mL |
Luminescent Reagent 2 | 6 mL |
Wash Solution (10x) | 100 mL |
Sample Buffer 1 | 0.6 mL |
Sample Buffer 2 | 30 mL |
Plate Seal | 3 sheets |
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific