Topic: Large-scale Expansion of Human Mesenchymal Stromal/Stem Cells 
Presenter: Amaris Castanon, Field Application Scientist, FUJIFILM Biosciences

Cell therapy developers focused on regenerative medicine rely on human mesenchymal stromal/stem cells (MSCs) for their ability to expand and differentiate across a variety of cell types. 

To generate high-quality MSCs in sufficient quantities for large-scale clinical trials, many cell therapy manufactures are moving from static to dynamic systems. MSC expansion in a closed sterile environment can help minimize risk of contamination, reduce production costs, and streamline the transition from research to clinical scale.

Cell therapy developers focused on regenerative medicine rely on human mesenchymal stromal/stem cells (MSCs) for their ability to expand and differentiate across a variety of cell types. 

To generate high-quality MSCs in sufficient quantities for large-scale clinical trials, many cell therapy manufacturers are moving from static to dynamic systems. MSC expansion in a closed sterile environment can help minimize risk of contamination, reduce production costs, and streamline the transition from research to clinical scale.

Introducing a closed system, serum- and xeno-free, scalable solution for MSC expansion―PRIME-XV MSC XSFM Dual Component Kit. This off-the-shelf product includes media and supplement in an easy-to-use kit, designed for closed, automated, and hollow-fiber systems.  

Discover how PRIME-XV MSC XSFM Dual Component Kit can:

• Maximize MSC expansion to clinically relevant doses
• Reduce risk of contamination with closed-system processing
• Minimize variability in MSC expansion in xeno- and serum-free conditions
• Simplify and expedite MSC expansion at scale