deScale Solution

SCALEVIEW-S series are reagent used for ScaleS. ScaleS is tissue clearing method developed by Dr. Atsushi Miyawaki etc. This method uses solutions with mainly urea. deScale Solution is used in the washing process of ScaleS.

The tissue is made transparent and adjusted RI for microscopic observation by soaking in 6 kinds of solutions (SCALEVIEW-S0, SCALEVIEW-S1, SCALEVIEW-S2, SCALEVIEW-S3, SCALEVIEW-S4, SCALEVIEW-SMt). 2mm section can be made transparent in 1 day using the reagents.

The method can make a transparent tissue keeping the structure of proteins. Therefore it is possible to observe the tissue expressing fluorescent proteins, and to label by antibody and/or fluorescent dye after tissue clearing. It's also applicable to not only mouse and rat brain but also human after dye. The transparent tissue can be observed for electric microscope or confocal microscope.

ScaleS is higher transparency than ScaleA2.

See the following website for more details: https://labchem-wako.fujifilm.com/us/category/00593.html

Tissue Optical Clearing Reagent

Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific.

• For research use only. Not for use in diagnostic procedures.
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