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This product is for research use only. Do not administer it to human.
This is a Wnt signaling inhibitor. IWR-1 stabilizes a complex (consisting of Axin2, Apc, Ck1 and Gsk3β) that degrades beta catenin and promotes decomposition of beta catenin.
Features
It has been examined by endotoxins and mycoplasma tests.
for Cell Culture
Specification Assay: | 98.0+% (HPLC) |
Manufacturer: | FUJIFILM Wako Pure Chemical Corporation |
CAS RN: | 1127442-82-3 |
Molecular Formula: | C25H19N3O3 |
Molecular Weight: | 409.44 |
Appearance: | White - pale yellow, crystalline powder - powder |
Solubility: | Soluble in Acetonitrile(1mg/mL), DMSO(10mg/mL), Aceton(10mg/mL), Ethanol99.5(0.2mg/mL) Soluble in Acetonitrile, Acetone, and hyl Sulfoxide. Practically insoluble in Water |
Specific Rotation: | -3.0 - +3.0 degrees (20 degrees C/D)(c=0.1,CH3CN) |
Purity: | Endotoxins: <0.25EU/mg |
Preacautions for Use: | It is not sterilized product. Please use it with sterilized filter after dissolving. |
Alias: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide endo-IWR-1 |
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific.