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This product is for research use only. Do not administer it to human.
This is a GSK-3β (glycogen synthase kinase 3β) inhibitor, and its selectivity is higher than any other GSK-3β inhibitor reported to date.
This product does not show cross-reactivity to CDKs (Cyclin-dependent kinases).
It has been reported that differentiation can be suppressed with high efficiency when ES cells are cultured in a medium containing CHIR99021/PD0325901.
[Ying, QL., et al.: Nature, 453, 519 (2008).]
for Cell Culture
Specification Assay: | 97.0+% (HPLC) |
Manufacturer: | FUJIFILM Wako Pure Chemical Corporation |
CAS RN: | 252917-06-9 |
Molecular Formula: | C22H18Cl2N8 |
Molecular Weight: | 465.34 |
GHS: | Danger |
Appearance: | White - pale brown, crystalline powder - powder |
Purity: | Bacterial endotoxins : <0.25EU/mg |
Alias: | 6-{2-[4-(2,4-Dichloro-phenyl)-5-(5-methyl-1H-imidazol-2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile |
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific.