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This product is for research use only. Do not administer it to humans.
This is a Wnt signaling inhibitor. IWR-1 stabilizes a complex (consisting of Axin2, Apc, Ck1 and Gsk3β) that degrades beta catenin and promotes decomposition of beta catenin.
It has been examined by endotoxins and mycoplasma tests.
for Cell Culture
| Specification Assay: | 98.0+% (HPLC) |
| Manufacturer: | FUJIFILM Wako Pure Chemical Corporation |
| CAS RN: | 1127442-82-3 |
| Molecular Formula: | C25H19N3O3 |
| Molecular Weight: | 409.44 |
| Appearance: | White - pale yellow, crystalline powder - powder |
| Solubility: | Soluble in Acetonitrile(1mg/mL), DMSO(10mg/mL), Aceton(10mg/mL), Ethanol99.5(0.2mg/mL) Soluble in Acetonitrile, Acetone, and hyl Sulfoxide. Practically insoluble in Water |
| Specific Rotation: | -3.0 - +3.0 degrees (20 degrees C/D)(c=0.1,CH3CN) |
| Purity: | Endotoxins: <0.25EU/mg |
| Preacautions for Use: | It is not sterilized product. Please use it with sterilized filter after dissolving. |
| Alias: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide endo-IWR-1 |
Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Biosciences.